Independent GLP-1 guide

Clear information before you choose a GLP-1 provider

Learn how GLP-1 medicines work, understand the safety questions to discuss with a clinician, and compare three telehealth services without exaggerated promises.

No miracle claimsOutcomes vary by person and treatment.
Commercial links disclosedWe may earn a commission from featured providers.
Sources you can inspectMedical claims link to FDA and NIH materials.

Featured comparison

Three telehealth providers to compare

These services differ in their care model and support. Inclusion is commercial and does not mean a provider is medically appropriate for you.

1

Featured provider

SkinnyRx

A telehealth weight-management service connecting patients with licensed clinicians who determine whether prescription treatment is appropriate.

  • Online medical intake
  • Clinician-directed treatment
  • Ongoing patient support

Advertised treatment pricing

Injectable semaglutideIntroductory price$99 first month
Injectable tirzepatideIntroductory price$99 first month
Oral semaglutideIntroductory price$149 first month
Oral tirzepatideIntroductory price$199 first month

Pricing notice: Pricing, promotions and available treatments can change at any time. Prices may depend on the medication, formulation, dose, plan length or introductory offer. Always verify current pricing and total charges directly with the provider before purchasing.

2

Metabolic care option

Enhance.MD

A metabolic wellness platform whose affiliated clinicians offer telehealth evaluation, ongoing care and laboratory monitoring.

  • Clinician consultation
  • Laboratory monitoring
  • Coaching and follow-up

Advertised treatment pricing

Injectable semaglutide12-month plan; billed every 48 weeks. Current first-order offer: $100 off plans of 3+ months or $50 off a 1-month plan.From $212/month
Injectable tirzepatideProvider-published starting priceFrom $280/month

Pricing notice: Pricing, promotions and available treatments can change at any time. Prices may depend on the medication, formulation, dose, plan length or introductory offer. Always verify current pricing and total charges directly with the provider before purchasing.

3

Streamlined option

TrimRx

A telehealth weight-management program offering medical review and ongoing check-ins when prescription treatment is considered appropriate.

  • Online assessment
  • Medical review
  • Ongoing check-ins

Advertised treatment pricing

GLP-1 injectionsCurrent promotional landing-page priceFrom $149
GLP-1 + GIP injectionsCurrent promotional landing-page priceFrom $249

Pricing notice: Pricing, promotions and available treatments can change at any time. Prices may depend on the medication, formulation, dose, plan length or introductory offer. Always verify current pricing and total charges directly with the provider before purchasing.

Affiliate disclosure: We may receive compensation if you use a featured link. Compensation does not change the medical information on this site. How our commercial relationships work.

The medical foundation

GLP-1 is a medication class—not a single product

GLP-1 receptor agonists mimic a hormone involved in appetite, food intake and blood-glucose regulation. Some medicines are FDA-approved for chronic weight management, some for type 2 diabetes, and compounded versions are not FDA-approved.

A clinician should consider your health history, other medicines, potential benefits and possible adverse effects before prescribing.

Read the complete introduction

Explore the guide

Answers for each stage of your research

Use these guides to understand treatment, prepare for an injection and evaluate provider claims before making a decision.